![]() Dietary fat intake, fat quality, and cholesterol intake regulate values of serum lipids in children the same way they do in adults. However, fears that low intake of saturated fat and cholesterol might influence growth and cognitive development have led to the exclusion of infants and young children from these recommendations, 1 although numerous arguments support early-onset prevention of children’s exposure to environmental coronary heart disease risk factors. ![]() Extensive dietary-fat–oriented and other lifestyle recommendations have been delivered to the general community to manage this epidemic. Puberty markedly influences serum cholesterol concentrations.Ītherosclerosis develops as a result of a lifelong process often leading to coronary heart disease. Mean concentrations of total and high-density lipoprotein cholesterol decreased from ≈4.5 and ≈1.4 mmol/L, respectively, in Tanner stage 1 (prepubertal) boys to ≈3.9 and ≈1.1 mmol/L in Tanner stage 4 (late pubertal) boys.Ĭonclusions- Repeated dietary counseling remains effective in decreasing saturated fat and cholesterol intake and serum cholesterol values at least until 14 years of age. The cholesterol values decreased as puberty progressed. The 2 study groups showed no difference in growth, body mass index, pubertal development, or age at menarche (median, 13.0 and 12.8 years in the intervention and control girls, respectively P=0.52). Boys had lower total and low-density lipoprotein cholesterol concentrations than girls throughout childhood ( P<0.001), and the intervention effect on serum cholesterol concentration was larger in boys than girls. Saturated fat intakes, serum total cholesterol, and low-density lipoprotein cholesterol values were lower ( P<0.001) in the intervention than in control children during the 14 years, whereas high-density lipoprotein cholesterol values in the 2 study groups showed no difference. Dietary intakes, serum cholesterol values, somatic growth, and development were followed up throughout childhood and adolescence. Methods and Results- In the randomized prospective Special Turku Coronary Risk Factor Intervention Project (STRIP), a low-saturated-fat, low-cholesterol diet was introduced to intervention infants (n=540) at 7 months of age, and control children (n=522) received an unrestricted diet. The aims of the present study were to evaluate the effect of low-saturated-fat, low-cholesterol dietary counseling on fat intakes, growth, serum cholesterol values, and pubertal development in children and adolescents. Customer Service and Ordering Informationīackground- Atherosclerosis development might be delayed or prevented by dietary measures.Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
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